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COMPOSITIONS LIPOSOMALES CONTENANT DES INHIBITEURS DU PROTEASOME A BASE D'EPOXYCETONE
专利权人:
INC.;ONYX THERAPEUTICS
发明人:
CHU, KATHERINE A.,CHAN, ELENA T.,FANG, YING,JUMAA, MOUHANNAD,KIRK, CHRISTOPHER JUSTIN,MUCHAMUEL, TONY MARCEL,WANG, ZHENGPING,JIANG, JING,JONES, JEFFREY JOSEPH
申请号:
CA2879208
公开号:
CA2879208A1
申请日:
2013.07.17
申请国别(地区):
CA
年份:
2014
代理人:
摘要:
Liposomal compositions comprising peptide epoxyketone compounds are described, as well as methods of making and using such liposomal compositions. These liposomal compositions provide prolonged drug exposure (relative to non-liposomal compositions comprising peptide epoxyketone compounds) without significantly affecting biodistribution of the drug. Tolerability of peptide epoxyketone compounds was also enhanced when formulated in the liposomal compositions.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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