CHU, KATHERINE A.,CHAN, ELENA T.,FANG, YING,JUMAA, MOUHANNAD,KIRK, CHRISTOPHER JUSTIN,MUCHAMUEL, TONY MARCEL,WANG, ZHENGPING,JIANG, JING,JONES, JEFFREY JOSEPH
申请号:
CA2879208
公开号:
CA2879208A1
申请日:
2013.07.17
申请国别(地区):
CA
年份:
2014
代理人:
摘要:
Liposomal compositions comprising peptide epoxyketone compounds are described, as well as methods of making and using such liposomal compositions. These liposomal compositions provide prolonged drug exposure (relative to non-liposomal compositions comprising peptide epoxyketone compounds) without significantly affecting biodistribution of the drug. Tolerability of peptide epoxyketone compounds was also enhanced when formulated in the liposomal compositions.