THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS
发明人:
Terry Vanden Hoek,Xiangdong Zhu,Jing Li
申请号：
US15769132
公开号：
US20180296640A1
申请日:
2016.11.07
申请国别(地区):
US
年份:
2018
代理人:
摘要：
Modified peptides based on C-terminal PDZ binding domains of PTEN and PHLPP, or PDK1 interacting fragment of PKN2 are described as are methods of using the modified peptides for blocking the activity of PTEN, PHLPP and PKN2 and treating sudden cardiac arrest. A method for guiding treatment of cardiac arrest based on sorbitol or taurine levels is also provided.
