amanita toxin derivatives and their conjugation to a cell binding molecule

• 收藏
• 分享

专利权人:

HANGZHOU DAC BIOTECH CO.; LTD

发明人:

CAO, MINJUN,GAI, SHUN,GUO, HUIHUI,GUO, ZIXIANG,HUANG, YUANYUAN,JIA, JUNXIANG,LI, WENJUN,LIN, CHEN,TONG, QIANQIAN,XIE, HONGSHENG,XU, YIFANG,YANG, CHENGYU,YANG, QINGLIANG,YE, HANGBO,ZHAO, LINYAO,ZHAO, R

申请号：

BR112018071465

公开号：

BR112018071465A2

申请日:

2016.04.20

申请国别(地区):

BR

年份:

2019

代理人:

摘要：

Amanita toxin derivatives of formula (I) wherein formula (a) is (1) r1, r2, r3, r4, r5, r6, r7, r8, r9, r10, x, l, m, n and q are defined herein. the preparation of derivatives. therapeutic use of derivatives in the targeted treatment of cancer, autoimmune disorders and infectious diseases.derivados de toxinas de amanita de formula (i), em que, formula (a) r1, r2, r3, r4, r5, r6, r7, r8, r9, r10, x, l, m, n e q são aqui definidos. a preparação dos derivados. o uso terapêutico dos derivados no tratamento direcionado de câncer, distúrbios autoimunes e doenças infecciosas.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/