КЭМПБЕЛЛ Кэри В. (US),КЛИК Роберт Л. (US),КАЛЛИ Эдвард Х. (US),ХЕЙКСЕН Питер (US),ХОЛЛАНД Тереза А. (US),КРАНЦЛЕР Тейн Л. (US),ЛИ Мэй (US),СТЕЙНХАУС Брюс М. (US),ТРАПП Бенджамин М. (US),ТРИБЗ Томас Г.
申请号：
RU2015112236
公开号：
RU2015112236A
申请日:
2013.09.05
申请国别(地区):
RU
年份:
2016
代理人:
摘要：
1. A medical device comprising a. expandable element with an outer surface； and b. a shell containing a constricted member located around the expandable member c. moreover, when expanding the expandable element, the constricted element is configured to extend and decrease in width, thereby revealing at least a portion of the outer surface. The medical device according to claim 1, wherein the constricted element is at least one oriented spirally, longitudinally or circumferentially around the expandable element. The medical device according to claim 1, wherein the constricted element has a tubular shape with a lumen. The medical device of claim 3, wherein the tubular shape is wrapped in a spiral. The medical device according to claim 1, which further comprises a coating containing a therapeutic agent located inside the lumen of a tubular form. The medical device according to claim 1, which further comprises a coating containing a therapeutic agent located around the expandable element. The medical device of claim 1, wherein the coating comprises at least one compound selected from the group consisting of benzethonium chloride, polyethylene glycol, poloxamer, sodium salicylate and hydroxypropyl-β-cyclodextrin. Medical device according to any one of paragraphs. 5 or 6, in which the therapeutic agent is a hydrophilic agent. Medical device according to any one of paragraphs. 5 or 6, in which the therapeutic agent is a hydrophobic agent 10. Medical device according to any one of paragraphs. 5 or 6, in which the constricted element contains a permeable microstructure, which is configured to limit mass transfer1. Медицинское устройство, содержащееa. расширяемый элемент с наружной поверхностью； иb. оболочку, содержащую сужаемый элемент, расположенный вокруг расширяемого элемента；c. причем при расширении расширяемого элемента сужаемый элемент выполнен с возможностью удлинения и уменьшения по ширине, тем самым раскрывая по меньшей мере участок наружной поверхности.2. Медицинск
