Patrick Ruane,Cameron Wilson,Steven Ummel,Arlene Alcantara,Jackie Joe Hancock,Qi Zhan
申请号:
US14162900
公开号:
US20150209555A1
申请日:
2014.01.24
申请国别(地区):
US
年份:
2015
代理人:
摘要:
A method and device for local delivery of a water-insoluble therapeutic agent to the tissue of a normal or diseased body lumen is disclosed. An expandable structure of a medical disposable device, such as a balloon of a balloon catheter, is coated with a non-durable coating which includes an amphiphilic polymer or copolymer, in embodiments polyethylene glycol, having a substantially water-insoluble therapeutic agent dispersed therein. In some embodiments, the coating may also include iodine. The medical disposable device is inserted into a body lumen, and expanded to contact the non-durable coating against the body lumen and deliver the substantially water-insoluble therapeutic agent to the body lumen tissue.