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Local delivery of water-soluble or water-insoluble therapeutic agents to the surface of body lumens
专利权人:
发明人:
Eugene T. Michal,Matthew J. Pollman
申请号:
US14852790
公开号:
US09603973B2
申请日:
2015.09.14
申请国别(地区):
US
年份:
2017
代理人:
摘要:
A method and device for local delivery of a water-insoluble therapeutic agent to the tissue of a normal or diseased body lumen is disclosed. An expandable structure of a medical disposable device, such as a balloon of a balloon catheter, is coated with a non-durable coating which comprises poly(HEMA) complexed with iodine and has a substantially water-insoluble therapeutic agent dispersed therein. The medical disposable device is inserted into a body lumen, and expanded to contact the non-durable coating against the body lumen and deliver the substantially water-insoluble therapeutic agent to the body lumen tissue.
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