THE SCRIPPS RESEARCH INSTITUTE, LA JOLLA;THE GOVERNMENT OF THE UNITED STATES OF AMERICA, ROCKVILLE
发明人:
CHERESH, DAVID A.,ELICEIRI, BRIAN,SCHWARTZBERG, PAMELA L.
申请号:
HU0102614
公开号:
HU227985B1
申请日:
1999.05.28
申请国别(地区):
HU
年份:
2012
代理人:
摘要:
The present invention describes methods for modulating angiogenesis in tissues using Src protein, modified Src protein, and nucleic acids encoding for such. Particularly the invention describes methods for inhibiting angiogenesis using an inactive Src protein, or nucleic acids encoding therefor, or for potentiating angiogenesis using an active Src protein, or nucleic acids encoding therefor. The invention also describes the use of gene delivery systems for providing nucleic acids encoding for the Src protein, or modified forms thereof.