The subject of the present invention is to provide a compound having anti-inflammatory activity, a pharmacally acceptable salt, etc.The solution of the present invention is a compound of formula (1) or its pharmacally acceptable salt.[expressions]A: benzene, etc., such as e: - CH.sub.2 -, G: 5 membered aromatic heterocycles, such as X: cyclohexane, j: 5 membered aromatic heterocycles, such as y: phenyl group, R1, R2, R3, halogen atoms, R4: C1-C6 alkyl groups, R4: C1-C6 alkyl groups, R5: hydrogen atoms such as r6a, R6b, R6C, r6d: R7: hydrogen atoms such as R7: hydrogen atoms, R8: hydrogen atoms, N1, N2, n 3:1本発明の課題は、抗炎症作用を有する化合物、その薬理上許容される塩等を提供すること。本発明の解決手段は、一般式(1)の化合物又はその薬理上許容される塩。[式中の記号は以下に定義される。A:ベンゼン等、E:-CH2-等、G:5員芳香族複素環等、X:シクロヘキサン等、J:5員芳香族複素環等、Y:フェニル基等、R1、R2、R3:ハロゲン原子等、R4:C1-C6アルキル基等、R5:水素原子等、R6a、R6b、R6c、R6d:水素原子等、R7:水素原子等、R8:水素原子等、n1、n2、n3:1等]