SPINNAKER BIOSCIENCES, INC.; INC.;MASSACHUSETTS INSTITUTE OF TECHNOLOGY;THE REGENTS OF THE UNIVERSITY OF CALIFORNIA;SPINNAKER BIOSCIENCES
发明人:
SAILOR, MICHAEL J.,KANG, JINYOUNG,JOO, JINMYOUNG,ANGLIN, EMILY,KWON, ESTER,SKALAK, MATTHEW,BHATIA, SANGEETA
申请号：
CA3021001
公开号：
CA3021001A1
申请日:
2017.04.14
申请国别(地区):
CA
年份:
2017
代理人:
摘要：
Compositions useful in the controlled delivery of therapeutic agents and their methods of preparation and use are provided. The compositions comprise an optionally oxidized porous silicon core, a layer on the surface of the porous silicon core that comprises a metal silicate, and a therapeutic agent. The compositions optionally further comprise one or more targeting agents and/or cell-penetrating agents to enable the particles to target and enter cells or tissues of interest in a treated subject.
