Spinnaker Biosciences Inc.;The Regents of the University of California;Massachusetts Institute Of Technology
发明人:
SAILOR, Michael J.,KANG, Jinyoung,JOO, Jinmyoung,ANGLIN, Emily,KWON, Ester,SKALAK, Matthew,BHATIA, Sangeeta
申请号：
EP17783317
公开号：
EP3442540A4
申请日:
2017.04.14
申请国别(地区):
EP
年份:
2019
代理人:
摘要：
Compositions useful in the controlled delivery of therapeutic agents and their methods of preparation and use are provided. The compositions comprise an optionally oxidized porous silicon core, a layer on the surface of the porous silicon core that comprises a metal silicate, and a therapeutic agent. The compositions optionally further comprise one or more targeting agents and/or cell-penetrating agents to enable the particles to target and enter cells or tissues of interest in a treated subject.
