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Związki spiro-oksindolowe i ich zastosowanie jako środków terapeutycznych
专利权人:
Xenon Pharmaceuticals Inc.
发明人:
CHAFEEV, MIKHAIL,CHOWDHURY, SULTAN,FRASER, ROBERT,FU, JIANMIN,KAMBOJ, RAJENDER,HOU, DUANJIE,LIU, SHIFENG,BAGHERZADEH, MEHRAN SEID,SVIRIDOV, SERGUEI,SUN, SHAOYI,SUN, JIANYU,CHAKKA, NAGASREE,HSIEH, TOM,CHAFEEV MIKHAIL,CHOWDHURY SULTAN,FRASER ROBERT,FU JIANMIN,KAMBOJ RAJENDER,HOU DUANJIE,LIU SHIFENG,BAGH
申请号:
PL06750402
公开号:
PL1888595T3
申请日:
2006.04.11
申请国别(地区):
PL
年份:
2012
代理人:
摘要:
This invention is directed to spiro-oxindole compounds of formula (I): wherein k, j, Q, R 1 , R 2a , R 2b , R 2c , R 2d , R 3a , R 3b , R 3c , and R 3d are as defined herein, as a stereoisomer, enantiomer, tautomer thereof or mixtures thereof; or a pharmaceutically acceptable salt, solvate or prodrug thereof, which are useful for the treatment and/or prevention of sodium channel-mediated diseases or conditions, such as pain. Pharmaceutical compositions comprising the compounds and methods of preparing and using the compounds are also disclosed.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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