The applicator (1) related to the present invention is provided with a flexible sheath (4) longer than the overall length of an instrument channel of a flexible endoscope (2) an operation part (3) used outside the instrument channel a deployed section (11A) that can be made to protrude from the front end of the sheath by operating the operation part and to pierce a tissue a tissue fastening tool (21, 61, 62, 63, 64, 65, 66, 81, 91) made of a superelastic wire formed in coil shape and housed inside the deployed section in a substantially extended condition and a pusher (22) that pushes out the tissue fastening tool from the deployed section when the operation part is operated.
