Nancy Yuk-Yu Ip;Fanny Chui-Fun Ip;Yueqing Hu;Wen Cai Ye
发明人:
Nancy Yuk-Yu Ip,Fanny Chui-Fun Ip,Yueqing Hu,Wen Cai Ye
申请号：
US13344393
公开号：
US20130012462A1
申请日:
2012.01.05
申请国别(地区):
US
年份:
2013
代理人:
摘要：
The present invention provides therapeutically active compounds and compositions as NMDA and MC receptor antagonists, which are useful in preventing and treating central nervous system disorders by inhibiting over-activation of NMDA and/or MC receptors. In one aspect, the present invention provides methods of treating and/or preventing neurodegenerative diseases and neuropathological disorders, methods of providing neuroprotection under stress conditions such as a stroke, methods of enhancing the brain's cognitive functions and methods of treating depression, anxiety and cachexia induced by a chronic disease in mammals and humans.
