PASQUALI, IRENE I,CASAZZA, ANDREA A,SAUNDERS, MARK M,LOSI, ELENA E,‧帕斯瓜利,‧卡薩薩,‧桑德斯,‧洛斯
申请号:
HK16104300.9
公开号:
HK1216302A
申请日:
2016.06.08
申请国别(地区):
HK
年份:
2016
代理人:
摘要:
The present invention relates to a process for preparing a crystalline micronised particulate of a glycopyrronium salt. The process involves suspending the drug in a water immiscible anti-solvent in which the drug has little or no solubility and micronizing the suspension. The resulting drug particles are physically stable with regard to agglomeration and/or aggregation on storage.