PROBLEM TO BE SOLVED: To provide an anti-thrombotic material capable of sufficiently exhibiting the anti-thrombotic properties of both an anti-thrombotic compound and a betaine compound while suppressing the elution of the compounds, in an anti-thrombotic compound and a betaine compound having both anti-platelet adhesion performance and anti-thrombin activation performance other than heparin or heparin derivatives.SOLUTION: Provided is an anti-thrombotic material comprising: a polymer an anti-thrombotic compound shown by the following general formula I) a covering material including a betaine compound a base material with a surface covered with the covering material, in which the polymer is covalent-bonded with the base material, and the anti-thrombotic compound and the betaine compound are covalent-bonded with the polymer.SELECTED DRAWING: NoneCOPYRIGHT: (C)2017,JPO&INPIT【課題】ヘパリン又はヘパリン誘導体以外で抗血小板付着性能と抗トロンビン活性化性能の双方を有する抗血栓性化合物及びベタイン化合物を、化合物の溶出を抑えたまま、抗血栓性化合物及びベタイン化合物の両方の抗血栓性を十分に発揮することができる抗血栓性材料を提供すること。【解決手段】本発明は、ポリマーと、以下の一般式(I)で示される抗血栓性化合物と、ベタイン化合物とを含む被覆材料と、該被覆材料によって表面が被覆された基材と、を備え、上記ポリマーは、上記基材と共有結合され、上記抗血栓性化合物及び上記ベタイン化合物は、上記ポリマーと共有結合されている、抗血栓性材料を提供する。【選択図】なし
