FIELD OF THE INVENTION The present invention relates to pharmaceutical compositions comprising an effective amount of an effective amount of an effective amount of a compound of the present invention for the treatment of colorectal cancer (CRC), phlorinic acid, 5-fluorouracil (5-FU) and irinotecan (FOLFIRI).본 발명은 결장직장암(CRC)의 치료에 유용한 아플리버셉트, 폴린산, 5-플루오로우라실(5-FU) 및 이리노테칸(FOLFIRI)을 포함하는 약제학적 조성물에 관한 것이다.