Liu, Xiaoxiang,Mandal, Mihirbaran,Iserloh, Ulrich,Stamford, Andrew W.,Wu, Yusheng,Zhu, Zhaoning,Cumming, Jared N.,Li, Guoqing
申请号：
AU2009239536
公开号：
AU2009239536B2
申请日:
2009.04.21
申请国别(地区):
AU
年份:
2012
代理人:
摘要：
In its many embodiments, the present invention provides provides certain 2-imino-3-methyl pyrrolo pyrimidone compounds, including compounds Formula (II): and include tautomers, steroisomers, or pharmaceutically acceptable salts or solvates of said compounds, stereoisomers, or said tautomers, wherein R, R, R, R, R, R, R, and R are each selected independently and as defined herein. Pharmaceutical compositions comprising one or more such compounds, and methods for their preparation and use in treating pathologies associated with amyloid beta (Aβ) protein, including Alzheimer's Disease, are also disclosed.
