Walter Hong-Shong Chang,Cheng-An Lin,Ting-Ya Yang,Chih-Hsien Lee,Ralph A. Sperling,Wolfgang J. Parak
申请号:
US13336774
公开号:
US20120100075A1
申请日:
2011.12.23
申请国别(地区):
US
年份:
2012
代理人:
摘要:
The present invention discloses a fluorescent gold nanocluster, comprising: a dihydrolipoic acid ligand (DHLA) on the surface thereof, wherein the fluorescent gold nanocluster generates fluorescence by the interaction between the dihydrolipoic acid ligand and the nanocluster and the particle diameter of the fluorescent gold nanocluster is between 0.5 nm and 3 nm, wherein the wavelength of the emission fluorescence of the fluorescent gold nanocluster is between 400 nm and 1000 nm. In addition, the fluorescent gold nanocluster is used as bioprobes and/or applied in fluorescent biological label, clinical image as contrast medium, clinical detection, clinical trace, and clinical treatment etc.