The present invention relates to a device for the hygienisation of medical instruments, in particular stethoscopes.In particular, the present invention relates to a hygienisation or sterilisation system (1) of a medical-healthcare instrument, comprising a hygienisation or sterilisation device (2) and a coupling member (3) associable to said medical-healthcare instrument, characterised in that the coupling between said coupling member (3) and said device (2) is actuated by magnetic coupling means.