LEE, BEOM JIN,이범진,JUNG, WON TAE,정원태,CHOI, YOUN WOONG,최연웅,NAM, KYU YEOL,남규열,CHO, SANG MIN,조상민,PARK, JIN HA,박진하
申请号：
KR1020120039708
公开号：
KR1020130117048A
申请日:
2012.04.17
申请国别(地区):
KR
年份:
2013
代理人:
摘要：
PURPOSE: A complex composition containing amlodipine and losartan is provided to minimize physical bond between amlodipine and losartan with high stability because the complex composition contains propyl gallate and to minimize formulation processes.CONSTITUTION: A complex composition for preventing and treating cardiovascular diseases contains amlodipine or a pharmaceutically acceptable salt thereof, losartan or a pharmaceutically acceptable salt thereof, and propyl gallate. The complex composition is a double-layer tablet comprising an amlodipine layer containing amlodipine or a pharmaceutically acceptable salt thereof and a losartan layer containing losartan or a pharmaceutically acceptable salt thereof.COPYRIGHT KIPO 2013[Reference numerals] (AA) Example 8 (BB) Example 9 (CC) Example 10 (DD) Example 11 (EE) Example 12 (FF) Example 13 (GG) Example 14 (HH) Example 15 (II) Example 16 (JJ) Example 17본 발명은 항산화제를 포함함으로써, 안정성이 향상된 암로디핀 및 로잘탄을 함유하는 복합제 조성물에 관한 것이다.
