PARK, JAE HYUN,朴宰贤,朴宰賢,TAFESSE, LAYKEA,塔菲斯 莱奇,塔菲斯 萊奇,塔菲斯 莱奇,塔菲斯 萊奇
申请号：
TW102146081
公开号：
TW201434836A
申请日:
2013.12.13
申请国别(地区):
TW
年份:
2014
代理人:
摘要：
The application is directed to compounds of Formula Iand pharmaceutically acceptable salts and solvates thereof, wherein R1-R4, Y, and Z are defined as set forth in the specification. The invention is also directed to use of compounds of Formula I to treat disorders responsive to the modulation of one or more opioid receptors, or as synthetic intermediates. Certain compounds of the present invention are especially useful for treating pain.本發明係關於式I化合物，及其醫藥上可接受之鹽和溶劑合物，其中R1-R4、Y和Z係如說明書中所提出之定義。本發明亦關於式I化合物用於治療對一或多種鴉片受體之調節有反應的病症或作為合成中間物的用途。本發明的特定化合物尤其有用於治療疼痛。
