The present invention relates to the pyrazinone derivatives of formula (I), and wherein R1, R2, R3, R4, R5, R6 and R7 are for example defined herein; Their preparation method contains their pharmaceutical composition and their purposes in the treatment.本發明涉及式(I)的吡嗪酮衍生物,其中R1、R2、R3、R4、R5、R6和R7如本申請中所定義;它們的製備方法、含有它們的藥物組合物和它們在治療中的用途。