An instrument lifting operation device including: an operation wire drawing mechanism configured to draw an proximal end of an operation wire connected to an instrument lifting piece and a braking mechanism configured to restrict movement of the operation wire toward the tip side, wherein the braking mechanism includes: a fixed wall and a spring arranged to be able to rotate about an axis together with an instrument lifting operation member in a state where the spring is elastically pressed against an inner circumferential surface of the fixed wall. When the instrument lifting operation member is operated to rotate about the axis, the wire coupling member rotates about the axis and the operation wire moves forward and backward in a state where the spring contacts and slides on the inner circumferential surface of the fixed wall to generate frictional resistance at a contacting part.