MERMOD, NICOLAS,GIROD, PIERRE ALAIN,BUCHER, PHILIPP,CALABRESE, DAVID,NGUYEN, DUC-QUANG,SAUGY, DAMIEN,PUTTINI, STEFANIA
申请号:
PL10178873
公开号:
PL2298898T3
申请日:
2004.10.22
申请国别(地区):
PL
年份:
2013
代理人:
摘要:
The present invention relates to purified and isolated DNA sequences having protein production increasing activity and more specifically to the use of matrix attachment regions (MARs) for increasing protein production activity in a eukaryotic cell. Also disclosed is a method for the identification of said active regions, in particular MAR nucleotide sequences, and the use of these characterized active MAR sequences in a new multiple transfection method.