The present invention relates to a composition for transferring protein, and to a method for transferring bioactive materials or proteins using the same. The composition for transferring proteins comprises porous silica nanoparticles having pores having average pore diameter of 1 nm or more and 100 nm or less and a functional group coupled with the inner or outer surfaces of the porous silica nanoparticles, and providing surficial negative charge or positive charge, or a ligand specifically bonded with proteins.COPYRIGHT KIPO 2016단백질 전달용 조성물 및 이를 이용한 생리활성 물질 또는 단백질의 전달 방법에 관한 것이다.