CASTANEDO, GEORGETTE,FENG, JIANWEN,MONTALBETTI, CHRISTIAN A.G.N.,STABEN, STEVEN
申请号：
HK15106658.3
公开号：
HK1206024A
申请日:
2015.07.13
申请国别(地区):
HK
年份:
2015
代理人:
摘要：
The invention relates to novel compounds of Formula I: wherein A1, A2, A3, A4, A5, A6, R2, R4, R5, R6, R7, R8 and subscripts m and n each has the meaning as described herein. Compounds of Formula I and pharmaceutical compositions thereof are useful in the treatment of disease and disorders in which undesired or over-activation of NF-kB signaling is observed.
