FENG, JIANWEN,STABEN, STEVEN,CASTANEDO, GEORGETTE,MONTALBETTI, CHRISTIAN A.G.N.
申请号：
CA2859454
公开号：
CA2859454A1
申请日:
2013.02.15
申请国别(地区):
CA
年份:
2013
代理人:
摘要：
The invention relates to novel compounds of Formula I: wherein A1, A2, A3, A4, A5, A6, R2, R4, R5, R6, R7, R8 and subscripts m and n each has the meaning as described herein. Compounds of Formula I and pharmaceutical compositions thereof are useful in the treatment of disease and disorders in which undesired or over-activation of NF-kB signaling is observed.
