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皮膚使用のための起泡性及び/又は洗浄性の組成物の眼球への刺激作用を減少する新規の方法
专利权人:
ソシエテ・デクスプロワタシオン・デ・プロデュイ・プール・レ・アンデュストリー・シミック・セピック
发明人:
ロソ、アリシア,アマルリ、シャンタ,タバッシ、ギー
申请号:
JP2009500894
公开号:
JP5378198B2
申请日:
2007.03.16
申请国别(地区):
JP
年份:
2013
代理人:
摘要:
Improving the ocular tolerance of a topical composition comprises incorporating a polyol-glycoside compound (I) in the composition. Improving the ocular tolerance of a topical composition comprises incorporating a polyol-glycoside compound (I) of formula R1-O-Gx-H in the composition. G : a reducing sugar like glucose, xylose, arabinose (all preferred), dextrose, saccharose, fructose, idose, gulose, galactose, (iso)maltose, maltotriose, lactose, cellobiose, mannose, ribose, lyxose, allose, altrose, dextran or tallose x : 1-5 R1 : CH2-(CHOH)n-CH2-OH or -(CH2-CHOH-CH2-O)m-H n : 2-4 and m : 1-3. Independent claims are included for: (1) a topical composition comprising (I) at 0.2-90 mass.%, an ester compound of formula [R2-O-(CH2-CH2-O)p-SO3]r-X at 2-99 mass.% and a solvent at 0-80 mass.% and (2) a process of preparing the concentrate mixing (I) and the ester compound under agitation, and optionally mixing the obtained mixture with the solvent. R2 : 6-22C, preferably 8-18C hydrocarbon p : 1 -10, preferably 2-4 r : 1-2 and X : (alkaline)earth metal cation, NH4+> or (tri)hydroxyethyl ammonium ion.
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