Mixed crystal agomelatine (Form-VIII), preparation method and use thereof and pharmaceutical composition containing same

• 收藏
• 分享

专利权人:

Shanghai Institute of Pharmaceutical Industry;Les Laboratoires Servier

发明人:

Huang, Yu,Long, Qing,Zhu, Xueyan,Shan, Hanbin,Yuan, Zhedong,Yu, Xiong

申请号：

AU2012231548

公开号：

AU2012231548A1

申请日:

2012.03.22

申请国别(地区):

AU

年份:

2013

代理人:

摘要：

The present invention provides a mixed crystal agomelatine (Form-VIII), the preparation method and use thereof and a pharmaceutical composition containing the same, wherein the mixed crystal mainly contains an agomelatine crystal form VI. The mixed crystal is stable and has good reproducibility, and is found through a stability test to be superior to a crystal form VI in terms of stability. Therefore, the Form-VIII of the present invention has an advantage in terms of preparation.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/