Mixed crystal agomelatine (form-VIII), preparation method and use thereof and pharmaceutical composition containing same

• 收藏
• 分享

专利权人:

SHANGHAI INSTITUTE OF PHARMACEUTICAL INDUSTRY;LES LABORATOIRES SERVIER

发明人:

ZHU Xueyan,SHAN Hanbin,YUAN Zhedong,YU Xiong,HUANG Yu,LONG Qing

申请号：

MYPI 2013701574

公开号：

MY166444A

申请日:

2012.03.22

申请国别(地区):

MY

年份:

2018

代理人:

摘要：

The present invention provides a mixed crystalline form VIII of agomelatine, its method of preparation, application and pharmaceutical composition. The said mixed crystal consists mainly of crystalline form VI of agomelatine. The said mixed crystalline form is stable and has good reproducibility. Through stability tests, it has been found to be superior to the crystalline form VI in terms of stability. As a result, the crystalline form VIII of the present invention possesses advantages in pharmaceutical preparation.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/