A multistage syringe includes a first barrel, a second barrel, a second barrel seal assembly, and a plunger assembly. The first barrel includes a first barrel channel and the second barrel includes a second barrel channel. The first barrel couples to the second barrel such that the first barrel channel aligns with the second barrel channel along a central axis. The plunger assembly includes a plunger coupled to a plunger handle. The plunger slidably couples with the first barrel channel along the central axis and the second barrel seal assembly slidably couples with the second barrel channel along the central axis. The plunger and the second barrel seal assembly cooperate to maintain a seal as the plunger transitions between a distal end of the multistage syringe and a proximal end of the multistage syringe.
