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CONJUGUE POLYMERE A BASE D'UN COMPLEXE DE PLATINE (II) COORDONNE A UN DERIVE DE SULFOXYDE
专利权人:
NIPPON KAYAKU KABUSHIKI KAISHA
发明人:
NAKAMURA, MASAHARU,FUKUDA, TSUYOSHI,YAMAKAWA, KEN,KATO, TAKUYA
申请号:
CA3009130
公开号:
CA3009130A1
申请日:
2016.12.16
申请国别(地区):
CA
年份:
2017
代理人:
摘要:
[Problem] A DDS preparation of a platinum complex showing the high antitumor effect and reduced side effects required as a medicine, that is, a clinically useable DDS preparation of a platinum complex characterized by being conjugated to a polymer carrier different from conventional ones, is desired. [Solution] Provided is a polymer conjugate of a platinum(II) complex, in which the sulfoxide group of a sulfoxide derivative introduced into a side chain carboxy group in a block copolymer having a polyethylene glycol structural moiety and a polyaspartic acid moiety or a polyglutamic acid moiety is coordinated to the platinum.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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