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PROCESS FOR PREPARING BENZOFURAN DERIVATIVES SUBSTITUTED AT POSITION 5
专利权人:
SANOFI
发明人:
BAILLY, FRÉDERIC,BON, XAVIER,VAYRON, PHILIPPE
申请号:
SG2013004338
公开号:
SG187565A1
申请日:
2011.07.20
申请国别(地区):
SG
年份:
2013
代理人:
摘要:
38AbstractPROCESS FOR PREPARING BENZOFURAN DERIVATIVES SUBSTITUTED AT POSITION 5The invention relates to a process for preparing benzofuran derivatives of general formula I, in which R represents a nitro or ester-COOR group, where R represents an alkyl group, R1 represents hydrogen or an alkyl group and R2 represents hydrogen, a halogen, a hydroxyl, haloalkyl, alkyl, alkoxy, dialkylaminoalkoxy or dialkylaminoalkyl group: by coupling the hydroxylamine with a diketone of general formula III: in order to form an oxime that is then cyclized by heating in order to form the desired compound.
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