Anthony Regina;Christian Che;Jean-Paul Castaigne;Michel Demeule
发明人:
Jean-Paul Castaigne,Michel Demeule,Christian Che,Anthony Regina
申请号：
US13500852
公开号：
US20120277158A1
申请日:
2010.10.05
申请国别(地区):
US
年份:
2012
代理人:
摘要：
The present invention is directed to conjugates that include a polypeptide capable of crossing the blood-brain barrier or entering one or more cell types attached to a transport vector, i.e., a composition capable of transporting an agent (e.g., a therapeutic agent). In certain cases, the polypeptides are directly conjugated to a lipid or polymeric vector to allow targeted application of a therapeutic agent to treat, for example, a cancer, a neurodegenerative disease, or a lysosomal storage disorder.
