SUZUKI, TAKASHI,铃木高,鈴木高,ABE, TETSUYA,阿部哲也,TAKAHASHI, RUI,高桥塁,高橋塁,ENDO, KOJI,远藤浩二,遠藤浩二,HAGURA, TOYOKI,土仓豊树,土倉豊樹,IWAI, HIDETAKA,岩井秀隆,HORIZUMI, TERUO,堀住辉男,堀住輝男,AOSAKI, TAISUKE,青崎泰辅,青崎泰輔,UDA, AK
申请号：
TW107147544
公开号：
TW201929668A
申请日:
2018.12.27
申请国别(地区):
TW
年份:
2019
代理人:
摘要：
The present invention provides a novel method for producing a composition containing a poorly water-soluble aromatic compound which is excellent in solubility of a poorly water-soluble aromatic compound. The method for producing a composition containing a poorly water-soluble aromatic compound includes the step (1) of obtaining a poorly water-soluble aromatic compound solution 1 comprising preparing (A) a poorly water-soluble aromatic compound, (B) a polyol, and (C) a step (1-1) of heat-treating the raw material of the aqueous medium, and a step of heat-treating the raw material of the heat-treated raw material at a temperature of less than 100 ° C under normal pressure to obtain a heat-treated liquid containing a poorly water-soluble aromatic compound ( 1-2)； and adding water to the water-insoluble aromatic compound solution 1 to obtain (A) a water-insoluble aromatic compound solution 2 having a concentration of the poorly water-soluble aromatic compound exceeding 25 ° C (2) In the above step (1), the content of the surfactant in the heat-treated raw material is 0.1% by mass or less, and the content of the (A) poorly water-soluble aromatic compound in the heat-treated raw material is less than (A) poorly water-soluble aromatic The saturation solubility of a compound at 25 ° C for a solvent of the same composition.本發明提供一種製造水難溶性芳香族化合物之溶解性優異之含有水難溶性芳香族化合物之組合物之新穎方法。 該含有水難溶性芳香族化合物之組合物之製造方法包括：獲得水難溶性芳香族化合物溶液1之步驟(1)，其包含製備含有(A)水難溶性芳香族化合物、(B)多元醇及(C)水性介質之加熱處理原料之步驟(1-1)，及對上述加熱處理原料於常壓下以未達100℃之溫度進行加熱處理，獲得含有水難溶性芳香族化合物之加熱處理液之步驟(1-2)；及於上述水難溶性芳香族化合物溶液1中添加水，獲得(A)水難溶性芳香族化合物之濃度超過25℃下之飽和溶解度之水難溶性芳香族化合物溶液2之步驟(2)， 於上述步驟(1)中，加熱處理原料中之界面活性劑之含量為0.1質量%以下，且加熱處理原料中之(A)水難溶性芳香族化合物之含量未達(A)水難溶性芳香族化合物對於同一組成之溶劑之25℃下之飽和溶解度。
