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P2X7 modulators
- 专利权人:
- Janssen Pharmaceutica NV
- 发明人:
- ALCAZAR VACA, Manuel Jesus,ANDRES GIL, Jose Ignacio,LETAVIC, Michael A.,RUDOLPH, Dale A.,SHIREMAN, Brock T.,STENNE, Brice M.,ZIFF, Jeannie M.
- 申请号：
- ES16176059
- 公开号：
- ES2666155T3
- 申请日:
- 2014.03.14
- 申请国别(地区):
- ES
- 年份:
- 2018
- 代理人:
- 摘要：
- A compound selected from the group consisting of: 7 - {[2-Chloro-3- (trifluoromethyl) phenyl] carbonyl} -4-phenyl-5,6,7,8-tetrahydropyrid [3,4-d] pyrimidine； 7 - [(2,3-Dichlorophenyl) carbonyl] -4-phenyl-5,6,7,8-tetrahydropyrid [3,4-d] pyrimidine； 7 - [(2,3-Dichlorophenyl) carbonyl] -N, N-dimethyl-4-phenyl-5, 6,7,8-tetrahydropyrido [3,4-d] pyrimidin-2-amine； 7 - {[2-Chloro-3- (trifluoromethyl) phenyl] carbonyl} -N, N-dimethyl-4-phenyl-5,6,7,8-tetrahydropyrido [3,4-d] pyrimidin-2-amine； 7 - [(2,3-Dichlorophenyl) carbonyl] -2-methyl-4-phenyl-5,6,7,8-tetrahydropyrid [3,4-d] pyrimidine； 7 - [(2,3-Dichlorophenyl) carbonyl] -4-phenyl-5,6,7,8-tetrahydropyrid [3,4-d] pyrimidin-2-amine； and 7 - {[2-Chloro-3- (trifluoromethyl) phenyl] carbonyl} -2-methyl-4-phenyl-5,6,7,8-tetrahydropyrido [3,4-d] pyrimidine.Un compuesto seleccionado del grupo que consiste de: 7-{[2-Cloro-3-(trifluorometil)fenil]carbonil}-4-fenil-5,6,7,8-tetrahidropirido [3,4-d]pirimidina； 7-[(2,3-Diclorofenil)carbonil]-4-fenil-5,6,7,8-tetrahidropirido[3,4-d]pirimidina； 7-[(2,3-Diclorofenil)carbonil]-N,N-dimetil-4-fenil-5 ,6,7,8-tetrahidropirido [3,4-d]pirimidin-2-amina； 7-{[2-Cloro-3-(trifluorometil)fenil]carbonil}-N,N-dimetil-4-fenil-5,6,7,8-tetrahidropirido [3,4-d]pirimidin-2-amina； 7-[(2,3-Diclorofenil)carbonil]-2-metil-4-fenil-5,6,7,8-tetrahidropirido[3,4-d]pirimidina； 7-[(2,3-Diclorofenil)carbonil]-4-fenil-5,6,7,8-tetrahidropirido[3,4-d]pirimidin-2-amina； y 7-{[2-Cloro-3-(trifluorometil)fenil]carbonil}-2-metil-4-fenil-5,6,7,8-tetrahidropirido [3,4-d]pirimidina.
- 来源网站：
- 中国工程科技知识中心
- 来源网址：
- http://www.ckcest.cn/home/
