ARIAGNO, SCOTT,HOUGHTON, FREDERICK CHARLES II,ROUSH, DANIEL E.
申请号:
ES11751767
公开号:
ES2550769T3
申请日:
2011.08.25
申请国别(地区):
ES
年份:
2015
代理人:
摘要:
Reconstitution system, comprising: (a) a housing (12, 20, 30) of generally cylindrical shape; (b) a first container (70) disposed within the housing (12) and configured to be displaced in axial direction in relation to the housing (12, 20, 30), the first container including a first hermetically sealed opening with a first cap hermetic closure (76); (c) a second container (80) disposed within the housing (12), which includes a second hermetically sealed opening with a second sealing cap (86), the first container (70) being disposed within the housing (12) in coincidence with the second container (80); (d) a transfer set assembly (40) disposed within the housing (12) between the first container (70) and the second container (80), the transfer set assembly being configured to fluidly access the first content through the first hermetic closure cap (76) of the first container (70) and to fluidly access the second contents through the second hermetic closure cap (86) of the second container (80); and (e) a trigger mechanism (100) configured to ensure that the transfer set assembly (40) accesses the first content of the first container (70) before accessing the second content of the second container (80), including the mechanism of firing a base part in contact with the second container (80) and multiple fingers extending from the base part, the firing mechanism being operable in an inactive state and in an activated state, and where: (i) in in the inactive state, the multiple fingers (102-106) separated in radial direction are coupled with the housing (12, 30) to prevent axial displacement of the second container (80) in relation to the housing (12, 20, 30) and the transfer set set (40); and (ii) in the activated state: (1) first, the first container (70) moves in an axial direction in relation to the housing (12) and the transfer set assembly (40) punctures the first sealing cap (76) to access the first content, and the first container (70) causes the firing fingers (102