The present disclosure provides a method and system for stimulating and monitoring intensity of pain experienced by one or more users. The method includes measuring the intensity of pain experienced by the one or more users on a pre-determined scale and augmented chart or physicians personal assessment using a plurality of one or more bio-markers, determining co-relation between the plurality of one or more bio-markers and the intensity of pain experienced by the one or more users, refining the co-relation between the plurality of one or more bio-markers and the intensity of pain experienced by the one or more users by learning from responses of one or more similar users, generating a pain profile for each of the one or more users and utilizing the learned information and the generated profile for monitoring, evaluating and treating the one or more users.