The present invention relates to extracts of artemia cysts in stress and the preparation method thereof. The present invention also relates to the use of the extracts of artemia cysts of the present invention in the treatment and/or prevention of skin abnormality.本發明關於逆境豐年蝦卵萃取物及其製備方法。本發明亦關於使用本發明之逆境豐年蝦卵萃取物於治療及/或預防皮膚異常之用途。(無元件符號說明)