It is an object of the present invention to provide an oriented collagen / apatite material wherein an orientation is controlled, and a method of the oriented collagen / apatite material wherein an orientation is controlled. A method of producing an orientated collagen / apatite material according to the present invention, is characterized in that the method comprises preparing a collagen having an orientation, seeding an osteoblast or a mesenchymal stem cell to produce and fix an apatite having an orientation similar to or almost the same as a direction of an orientation of the collagen on a surface and / or inside of the collagen. Furthermore, in a preferred embodiment of above mentioned method of producing an orientated collagen / apatite material according to the present invention, is characterized in that the osteoblast is an osteoblast like cell or an osteoblast obtained from a living organism.
