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製造三環凝血酶受體拮抗劑和含有這些受體拮抗劑的醫藥組合物
专利权人:
MERCK SHARP & DOHME CORP.
发明人:
CHACKALAMANNIL, SAMUEL,GREENLEE, WILLIAM J.,WANG, YUGUANG,XIA, YAN
申请号:
HK09102736.6
公开号:
HK1123302B
申请日:
2009.03.23
申请国别(地区):
HK
年份:
2013
代理人:
摘要:
Claimed is a process for the manufacture of compounds of the following general formula (II): wherein R x represent a group selected from COOCH 2 CH 3 , SO 2 CH 3 , CONHCH 3 , and COCH 3 , comprising the step of reacting the compound of the following formula (±-13) with a compound of the general formula R x -X, wherein X represents a leaving group and wherein R x is as defined above. Also claimed is a process for the manufacture of pharmaceutical compositions comprising compounds of the following formula (II) or pharmaceutically acceptable salts or solvates thereof.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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