Matthias Gromeier,John H. Sampson,Darell D. Bigner,Annick Desjardins,Henry S. Friedman
申请号：
US16505771
公开号：
US20190343904A1
申请日:
2019.07.09
申请国别(地区):
US
年份:
2019
代理人:
摘要：
Human clinical use of a chimeric poliovirus construct has demonstrated excellent anti-tumor effect. The mechanism of action is believed to involve both viral oncolysis as well as immune recruitment, both of which lead to necrosis in the area of the tumor. No adverse effects have been observed.
