GROMEIER, Matthias,SAMPSON, John H.,BIGNER, Darell D.,DESJARDINS, Annick,FRIEDMAN, Henry S.
申请号：
USUS2013/071246
公开号：
WO2014/081937A2
申请日:
2013.11.21
申请国别(地区):
US
年份:
2014
代理人:
摘要：
Human clinical use of a chimeric poliovirus construct has demonstrated excellent anti-tumor effect. The mechanism of action is believed to involve both viral oncolysis as well as immune recruitment, both of which lead to necrosis in the area of the tumor. No adverse effects have been observed.
