MALEK, NISAR,SASSE, FLORENZ,NICKELEIT, IRINA,FRANK, RONALD,HINKELMANN, BETTINA,STEINMETZ, HEINRICH
申请号:
CA2679435
公开号:
CA2679435C
申请日:
2008.02.27
申请国别(地区):
CA
年份:
2016
代理人:
摘要:
The present invention relates to the use of particular macrocycles that are inhibitors of the proteasomic degradation of p27, in particular Argyrin and derivatives thereof, preferably Argyrin A, for the treatment of proliferative diseases, such as cancer, as well as the derivatization of said macrocycles.