UTILISATION D'INHIBITEURS DE LA DEGRADATION DE P27, EN PARTICULIER L'ARGYRINE ET SES DERIVES, POUR LE TRAITEMENT DE MALADIES A EVOLUTION CHRONIQUE

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专利权人:

HELMHOLTZ-ZENTRUM FUER INFEKTIONSFORSCHUNG GMBH;MEDIZINISCHE HOCHSCHULE HANNOVER

发明人:

MALEK, NISAR,SASSE, FLORENZ,NICKELEIT, IRINA,FRANK, RONALD,HINKELMANN, BETTINA,STEINMETZ, HEINRICH

申请号：

CA2679435

公开号：

CA2679435C

申请日:

2008.02.27

申请国别(地区):

CA

年份:

2016

代理人:

摘要：

The present invention relates to the use of particular macrocycles that are inhibitors of the proteasomic degradation of p27, in particular Argyrin and derivatives thereof, preferably Argyrin A, for the treatment of proliferative diseases, such as cancer, as well as the derivatization of said macrocycles.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/