Protein complex excellent in cancer targeting and method for producing the same

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专利权人:

コリア・インスティテュート・オブ・サイエンス・アンド・テクノロジー

发明人:

イク チャン・クウォン,クイウォン・チョイ,クワン メユン・キム

申请号：

JP2009102647

公开号：

JP4920056B2

申请日:

2009.04.21

申请国别(地区):

JP

年份:

2012

代理人:

摘要：

The present invention relates to a protein conjugate having excellent tumor targeting capacity and a method for preparing the same, more precisely albumin-bile acid conjugate forming 30-500 nm nano-particles and forming self-aggregates in water system and a method for preparing the same. The albumin-bile acid conjugate of the present invention has excellent tumor targeting capacity and facilitates inclusion of a hydrophobic anticancer agent and can be combined with fore infrared ray fluorescent material. Therefore, this conjugate can be effectively used for the production of a novel nano-particle contrast agent or a nano-particle drug delivery system for the diagnosis and treatment of cancer.

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中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/