The medicine composition in order description below (A) or (B) includes 2 these chains RNA, to remedy the cancer or diabetes.(A) arrangement number 2, arrangement number 4, or 2 these chains RNA which possess the arrangement of arrangement number 8.2 these chains RNA which control the revelation of the gene which (B) human protoplasmic membrane shiaridaze (NEU3) possesses homologous arrangement in arrangement of portion of the gene which the cord/code is done at the same time, arrangement number 2, arrangement number 4, or being 2 these chains RNA of 20 - 30 bases which include the arrangement of arrangement number 8, human protoplasmic membrane shiaridaze (NEU3) the cord/code it does.下記の(A)または(B)の2本鎖RNAを含む、がんまたは糖尿病を治療するための医薬組成物。(A)配列番号2、配列番号4、または配列番号8の配列を有する2本鎖RNA。(B)ヒト形質膜シアリダーゼ(NEU3)をコードする遺伝子の一部の配列に相同な配列を有し、かつ、配列番号2、配列番号4、または配列番号8の配列を含む20~30塩基の2本鎖RNAであって、ヒト形質膜シアリダーゼ(NEU3)をコードする遺伝子の発現を抑制する2本鎖RNA。
