Pharmaceutical compositions comprising these Compounds, and Methods for using such compounds to Treat or prevent diseases or Disorders associated with abnormal or poorly Regulated kinase activity, particularly diseases or Disorders that involve or The abnormal Activation of b-raf.Claim 1: a compound of the formula (1): and where is selected from N and Cr6 R2, R3, R5 and R6 are independently selected from Hydrogen, halogeno, cyano, alkyl of 1 to 4 carbon ATOMS, alkyl of 1 to 4 carbon Atoms substituted by Halogen alkoxyl 1 4 carbon Atoms.Alkoxyl and 1 to 4 carbon Atoms substituted by Halogen with the condition that when R5 is Fluorine and R1 is selected from Hydrogen, x1r8a x1ox2r8a -, -, - X1c (OR) nr8ar8b x1nr8ax2r8b, -, - x1nr8ac (or x2or8b x1nr8as) and (OR) 0 - 2r8b, R3 and R6 are not both Hydrogen R4 is selected from - R9 and nr10r11 wherein R9 is selected from alkyl of 1 to 6 carbon Atoms.Cycloalkyl 3 to 8 Carbon ATOMS, hetero cycloalkyl 3 to 8 Carbon ATOMS, aryl and heteroaryl where the alkyl, cycloalkyl, aryl or Heterocyclic cycloalkyl, optionally substituted heteroaryl of R9 is 1 to 3 selected Radicals independently from haloge No, cyano, alkyl of 1 to 4 carbon ATOMS,Alkyl of 1 to 4 carbon Atoms substituted by Halogen, alkoxyl 1 to 4 carbon ATOMS, and alkoxyl 1 to 4 carbon Atoms substituted by Halogen and R10 and R11 is independently selected from Hydrogen and R9 R7 is selected from Hydrogen, alkyl of 1 to 4 \u00e1tom You carbonCycloalkyl 3 to 5 Carbon Atoms and hetero cycloalkyl 3 to 5 Carbon ATOMS, where the alkyl, cycloalkyl or Heterocyclic cycloalkyl R7 is optionally substituted with 1 to 3 selected Radicals independently from halogeno, cyano, hydroxyl, alkyl of 1 to 4 Volumes of carbon, alkyl of 1 to 4 carbon Atoms substituted by HalogenAlkoxyl 1 to 4 carbon ATOMS, and alkoxyl 1 to 4 carbon Atoms substituted by Halogen or tautomeros, pro drugs or stereoisomers, pharmaceutically acceptable salts thereof.Composiciones farmacéuticas que comprenden estos com
