POLYPEPTIDES, ACIDES NUCLÉIQUES ET LEURS UTILISATIONS

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专利权人:

Agency for Science; Technology and Research

发明人:

申请号：

EP14867236.3

公开号：

EP3077413A4

申请日:

2014.12.03

申请国别(地区):

EP

年份:

2017

代理人:

摘要：

We describe an ELABELA polypeptide comprising a sequence CXXXRCXXXHSRVPFP (SEQ ID NO: 1), in which X signifies an amino acid residue, such as a sequence selected from the group consisting of: SEQ ID NO: 2 to SEQ ID NO: 18, preferably CLQRRCMPLHSRVPFP (SEQ ID NO: 2), or a fragment, homolog, variant or derivative thereof, which polypeptide is capable of maintaining self-renewal and/or pluripotency of a stem cell.

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