ELLWANGER, COLLEEN,NOBLE, BRIAN,COKER, TIM,PLUNKETT, SEAN
申请号：
CA2894031
公开号：
CA2894031A1
申请日:
2013.12.03
申请国别(地区):
CA
年份:
2014
代理人:
摘要：
A device (100) for puncturing a capsule (219) to release a powdered medicament therefrom includes a chamber (210) for receiving the capsule. The capsule includes opposing domes and a cylindrical wall portion defined by a capsule wall radius r. The device further includes a mechanism (230) for puncturing at least one hole in at least one dome. A center of each hole is located within an annular puncture region situated at no less than 0.4r, and a total surface area of all puncture holes is between about 0.5% and about 2.2% of a total surface area of the capsule. The annular puncture region may, for example, be situated between about 0.4r and about 0.8r, or between about 0.4r and about 0.6r.
