A system having a dispenser, a cartridge receptacle and a cartridge. Thedispensercomprises a cartridge holder, which has at least one guide and/or twistprevention means forthe cartridge and/or the cartridge receptacle. The cartridge holder has acutout, which at leastpartially receives the cartridge and/or the cartridge receptacle. Thecartridge receptacle hasan inflow for a diluent, a mixing chamber, in which the diluent and a beveragesubstrateand/or foodstuff substrate are mixed, and an outflow. The cartridge is closedby means of amembrane, and the cartridge receptacle has a piercing means for perforatingthe membrane.The piercing means is provided in a manner aligned with the inflow and theoutflow.
